PUBLICATIONS

2024

Image processing tools for petabyte-scale light sheet microscopy data
X Ruan, M Mueller, G Liu, F Görlitz, TM Fu, DE Milkie, JL Lillvis, A Kuhn, …
Nature Methods, 1-11

A Cell Observatory to reveal the subcellular foundations of life
E Betzig
Nature Methods, 1-4

Neural space–time model for dynamic multi-shot imaging
R Cao, NS Divekar, JK Nuñez, S Upadhyayula, L Waller
Nature Methods, 1-6

PIEZO1-halotag hiPSC lines: A new tool to assay PIEZO1 localization and activity from single cells to tissue organoids
GA Bertaccini, E Evans, JL Nourse, GD Dickinson, G Liu, I Casanellas, …
Biophysical Journal 123 (3), 242a-243a

Neural space-time model for dynamic scene recovery in multi-shot computational imaging systems
R Cao, N Divekar, J Nuñez, S Upadhyayula, L Waller
bioRxiv, 2024.01. 16.575950

Nanoscale volumetric fluorescence imaging via photochemical sectioning
W Wang, X Ruan, G Liu, DE Milkie, W Li, E Betzig, S Upadhyayula, R Gao
bioRxiv, 2024.08. 01.605857

2023

Characterization, comparison, and optimization of lattice light sheets
G Liu, X Ruan, DE Milkie, F Görlitz, M Mueller, W Hercule, A Killilea, …
Science advances 9 (13), eade6623

Origin of wiring specificity in an olfactory map revealed by neuron type–specific, time-lapse imaging of dendrite targeting
KKL Wong, T Li, TM Fu, G Liu, C Lyu, S Kohani, Q Xie, DJ Luginbuhl, …
Elife 12, e85521

2022

Image-to-image regression with distribution-free uncertainty quantification and applications in imaging
AN Angelopoulos, AP Kohli, S Bates, M Jordan, J Malik, T Alshaabi, …
International Conference on Machine Learning, 717-730

Branched actin networks are organized for asymmetric force production during clathrin-mediated endocytosis in mammalian cells
M Jin, C Shirazinejad, B Wang, A Yan, J Schöneberg, S Upadhyayula, …
Nature communications 13 (1), 3578

2021

Adaptive wavelet distillation from neural networks through interpretations
W Ha, C Singh, F Lanusse, S Upadhyayula, B Yu
Advances in Neural Information Processing Systems 34, 20669-20682

A highly homogeneous polymer composed of tetrahedron-like monomers for high-isotropy expansion microscopy
R Gao, CC Yu, L Gao, KD Piatkevich, RL Neve, JB Munro, S Upadhyayula, …
Nature Nanotechnology 16 (6), 698-707

Cellular bases of olfactory circuit assembly revealed by systematic time-lapse imaging
T Li, TM Fu, KKL Wong, H Li, Q Xie, DJ Luginbuhl, MJ Wagner, E Betzig, …
Cell 184 (20), 5107-5121. e14

2020

Microscopy with adaptive optics
E Betzig, N Ji

Lamellar projections in the endolymphatic sac act as a relief valve to regulate inner ear pressure
IA Swinburne, KR Mosaliganti, S Upadhyayula, TL Liu, DGC Hildebrand, …
Elife 7, e37131

2018

Observing the cell in its native state: Imaging subcellular dynamics in multicellular organisms
T Liu*, S Upadhyayula* (*equal contribution), DE Milkie, V Singh, K Wang, …
Science 360 (6386), eaaq1392

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